ChloroquineV1, Main, Exploration, bibRecord, 001987

Leflunomide in subacute cutaneous lupus erythematosus – two sides of a coin

Identifieur interne : 001987 ( Main/Exploration ); précédent : 001986; suivant : 001988

Leflunomide in subacute cutaneous lupus erythematosus – two sides of a coin

Auteurs : Anke Suess [Allemagne] ; Michael Sticherling [Allemagne]

Source :

International Journal of Dermatology [ 0011-9059 ] ; 2008-01.

RBID : ISTEX:BDEBACF350073E50D773A9DBBBB79335AD697956

English descriptors

Teeft :
- Antibody ratio, Arch dermatol, Arthralgia, Cutaneous, Dermatol, Dermatology, Erythematosquamous, Erythematosus, Immunomodulatory, International journal, International society, Leflunomide, Leflunomide therapy, Leipzig, Lesion, Lupus, Lupus erythematosus, Oral prednisolone, Pharmacology, Prednisolone, Scle, Skin eruption, Skin lesions, Sticherling, Subacute, Subacute cutaneous lupus erythematosus, Subset, Suess, Systemic lupus erythematosus, Therapeutics.

Abstract

Background Subacute cutaneous lupus erythematosus (SCLE), a distinct clinical subset of lupus erythematosus, remains a therapeutic challenge, especially in cases resistant to topical and standard systemic therapy. Leflunomide, a novel antirheumatic drug, has shown efficacy in the treatment of systemic lupus erythematosus in pilot studies. Methods We report two patients with SCLE who demonstrated the spectrum of possible clinical responses to leflunomide therapy. Results One patient experienced a complete clinical remission of symptoms, whereas the other developed a massive skin reaction which was distinctly related to the commencement of leflunomide therapy. Conclusion To our knowledge, this is the first time that remission and deterioration of SCLE by leflunomide therapy have been described.

Url:

https://api.istex.fr/ark:/67375/WNG-Z7CZ0KNN-S/fulltext.pdf

DOI: 10.1111/j.1365-4632.2007.03333.x

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Istex, to step Corpus: 002514
to stream Istex, to step Curation: 002514
to stream Istex, to step Checkpoint: 000892
to stream Main, to step Merge: 001995
to stream Main, to step Curation: 001987

Le document en format XML

<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Leflunomide in subacute cutaneous lupus erythematosus – two sides of a coin</title>
<author><name sortKey="Suess, Anke" sort="Suess, Anke" uniqKey="Suess A" first="Anke" last="Suess">Anke Suess</name>
</author>
<author><name sortKey="Sticherling, Michael" sort="Sticherling, Michael" uniqKey="Sticherling M" first="Michael" last="Sticherling">Michael Sticherling</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:BDEBACF350073E50D773A9DBBBB79335AD697956</idno>
<date when="2008" year="2008">2008</date>
<idno type="doi">10.1111/j.1365-4632.2007.03333.x</idno>
<idno type="url">https://api.istex.fr/ark:/67375/WNG-Z7CZ0KNN-S/fulltext.pdf</idno>
<idno type="wicri:Area/Istex/Corpus">002514</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">002514</idno>
<idno type="wicri:Area/Istex/Curation">002514</idno>
<idno type="wicri:Area/Istex/Checkpoint">000892</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000892</idno>
<idno type="wicri:doubleKey">0011-9059:2008:Suess A:leflunomide:in:subacute</idno>
<idno type="wicri:Area/Main/Merge">001995</idno>
<idno type="wicri:Area/Main/Curation">001987</idno>
<idno type="wicri:Area/Main/Exploration">001987</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main">Leflunomide in subacute cutaneous lupus erythematosus – two sides of a coin</title>
<author><name sortKey="Suess, Anke" sort="Suess, Anke" uniqKey="Suess A" first="Anke" last="Suess">Anke Suess</name>
<affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>From the Department of Dermatology, University of Leipzig, Leipzig, Germany, and Department of Dermatology, University of Erlangen, Erlangen</wicri:regionArea>
<placeName><settlement type="city">Erlangen</settlement>
<region type="land" nuts="1">Bavière</region>
<region type="district" nuts="2">District de Moyenne-Franconie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Sticherling, Michael" sort="Sticherling, Michael" uniqKey="Sticherling M" first="Michael" last="Sticherling">Michael Sticherling</name>
<affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>From the Department of Dermatology, University of Leipzig, Leipzig, Germany, and Department of Dermatology, University of Erlangen, Erlangen</wicri:regionArea>
<placeName><settlement type="city">Erlangen</settlement>
<region type="land" nuts="1">Bavière</region>
<region type="district" nuts="2">District de Moyenne-Franconie</region>
</placeName>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j" type="main">International Journal of Dermatology</title>
<title level="j" type="alt">INTERNATIONAL JOURNAL OF DERMATOLOGY</title>
<idno type="ISSN">0011-9059</idno>
<idno type="eISSN">1365-4632</idno>
<imprint><biblScope unit="vol">47</biblScope>
<biblScope unit="issue">1</biblScope>
<biblScope unit="page" from="83">83</biblScope>
<biblScope unit="page" to="86">86</biblScope>
<biblScope unit="page-count">4</biblScope>
<publisher>Blackwell Publishing Ltd</publisher>
<pubPlace>Oxford, UK</pubPlace>
<date type="published" when="2008-01">2008-01</date>
</imprint>
<idno type="ISSN">0011-9059</idno>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0011-9059</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Antibody ratio</term>
<term>Arch dermatol</term>
<term>Arthralgia</term>
<term>Cutaneous</term>
<term>Dermatol</term>
<term>Dermatology</term>
<term>Erythematosquamous</term>
<term>Erythematosus</term>
<term>Immunomodulatory</term>
<term>International journal</term>
<term>International society</term>
<term>Leflunomide</term>
<term>Leflunomide therapy</term>
<term>Leipzig</term>
<term>Lesion</term>
<term>Lupus</term>
<term>Lupus erythematosus</term>
<term>Oral prednisolone</term>
<term>Pharmacology</term>
<term>Prednisolone</term>
<term>Scle</term>
<term>Skin eruption</term>
<term>Skin lesions</term>
<term>Sticherling</term>
<term>Subacute</term>
<term>Subacute cutaneous lupus erythematosus</term>
<term>Subset</term>
<term>Suess</term>
<term>Systemic lupus erythematosus</term>
<term>Therapeutics</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Background  Subacute cutaneous lupus erythematosus (SCLE), a distinct clinical subset of lupus erythematosus, remains a therapeutic challenge, especially in cases resistant to topical and standard systemic therapy. Leflunomide, a novel antirheumatic drug, has shown efficacy in the treatment of systemic lupus erythematosus in pilot studies. Methods  We report two patients with SCLE who demonstrated the spectrum of possible clinical responses to leflunomide therapy. Results  One patient experienced a complete clinical remission of symptoms, whereas the other developed a massive skin reaction which was distinctly related to the commencement of leflunomide therapy. Conclusion  To our knowledge, this is the first time that remission and deterioration of SCLE by leflunomide therapy have been described.</div>
</front>
</TEI>
<affiliations><list><country><li>Allemagne</li>
</country>
<region><li>Bavière</li>
<li>District de Moyenne-Franconie</li>
</region>
<settlement><li>Erlangen</li>
</settlement>
</list>
<tree><country name="Allemagne"><region name="Bavière"><name sortKey="Suess, Anke" sort="Suess, Anke" uniqKey="Suess A" first="Anke" last="Suess">Anke Suess</name>
</region>
<name sortKey="Sticherling, Michael" sort="Sticherling, Michael" uniqKey="Sticherling M" first="Michael" last="Sticherling">Michael Sticherling</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/ChloroquineV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001987 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001987 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    ChloroquineV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     ISTEX:BDEBACF350073E50D773A9DBBBB79335AD697956
   |texte=   Leflunomide in subacute cutaneous lupus erythematosus – two sides of a coin
}}

This area was generated with Dilib version V0.6.33.
Data generation: Wed Mar 25 22:43:59 2020. Site generation: Sun Jan 31 12:44:45 2021

	Serveur d'exploration Chloroquine
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration Chloroquine

Leflunomide in subacute cutaneous lupus erythematosus – two sides of a coin

Leflunomide in subacute cutaneous lupus erythematosus – two sides of a coin

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri